Restoration of Neural System Functionality using Multi-Electrode Arrays and Electronic Neurons

XD Investigator(s): 
Peter Andras
XD Institute: 
University of Newcastle
XD summary: 

 

The project aims to demonstrate through a pilot study the feasibility of the neuron-scale control of motor ganglia aimed to restore the functionality of damaged ganglia. This may pave the way toward a fundamentally new approach to neuro-functionality restoration intervention through electronic implants in the context of a range of diseases and disabling injuries (e.g. spinal cord damage).

We will use a prototype motor ganglion, the crab stomatogastric ganglion (STG), to demonstrate the proposed neuro-engineering technology. We will combine high speed optical recording of detailed neural activities, optogenetic temporary disabling of neurons, multi-electrode array (MEA) stimulation of neurons, and electronic implementation of computational model neurons to achieve our goal.

The proposed project is well aligned with the EPSRC healthcare  Technologies and Working Together themes and the priorities of ‘Novel treatment and therapeutic technologies’ and ‘Technologies for a healthy life-course’.
XD value: 
£59,607 (100% FEC)
XD Start Date: 
Mon, 01/07/2013
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